2nd December 2019
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9 Important Things To Consider For Your CBD Dosage

Cannabidiol usage and acceptance is still in its infancy, with only recently that experts have been able to fine-tune dosages and dosing schedules for medical marijuana products such as CBD oil

More countries across the world have been legalising medical marijuana but many doctors are still cautious about prescribing any marijuana-related products like CBD. There are a few reasons for this:

  1. Since there is no universal dose for all people, doctors can only recommend cannabinoids.
  2. Many medical schools don’t cover cannabidiol therapy as part of their curriculum.

Because recommended dosages are still unknown, the information stated below is intended to serve as a reference guide or starting point. Before using a medical cannabis product, you should consult with your doctor first. 

 

1. Not One Person is the Same

Many people don’t realize that there are quite a few different factors that make a big difference when CBD dosages are considered. Some of the variables include weight, metabolism, diet, genetics, product consistency, and more. That means that it is impossible to have one universal dosage for everyone.

Dosages have to be determined through rough estimates, and through time and experience. People who are new to cannabidiol start with the minimal suggested CBD dosage and gradually increase until they achieve their desired results.

Through studies (CBD Oil Review), it has been found that 25mg, taken twice daily, is a good starting point for many people. By increasing the amount of CBD by 25mg every 3-4 weeks, a person could potentially see symptom relief.

For the people that are complete novices to CBD, keeping track of their dosages and experiences in a notebook would definitely help. By narrowing down what their goals are and how they are feeling, they’ll be able to pinpoint the perfect dosage for themselves in no time.

From here, learning about CBD products and how dosages can affect different ailments and treatments is essential.

 

2. The Types of CBD Products

CBD oil comes in many different types of products and in what seems to be limitless forms and sizes. Each product is unique with its own CBD concentration and phytocannabinoids. The first step to finding the right dosage for yourself is learning about the products and which one would benefit you and your lifestyle the most. Here are some of the types of current products that contain CBD:

Topicals:

  • CBD-infused bath bombs
  • Balms, salves, lotions, soaps, shampoos
  • Transdermal patches

Ingestibles:

  • Edibles (gummies, cookies, brownies, etc.)
  • Portable dissolvable powders
  • Bottled waters
  • Chewing gum
  • Spritzers
  • CBD paste
  • Tinctures
  • Concentrated thick pastes

Smokeables:

  • eLiquids or vaping cartridges
  • Wax
  • Crystalline isolates

3. How to Use the Different Products

Some CBD products are very simple (tinctures) while some others take some time and effort (vaping cartridges). Here are some tips on how to use CBD in its many different forms:

CBD Concentrates: Concentrates will be very familiar to anyone that is used to smoking hash or other types of cannabis products. This form is extremely simple to use because all you need is a vaporizer or water pipe so you can sprinkle some of your CBD into it. From there, ignite and inhale!

CBD Vape Cartridges/Liquids: Vaping allows users to attain an immediate effect from usage. As far as products go, this method is the quickest way to deliver CBD benefits to the brain and body. This form is self-explanatory as you will need the eLiquid or vaping cartridges that contain the CBD oil, and also a vaporizer. To use this method, all you do is breathe in on the mouthpiece of the vaporizer for a few seconds, hold on the product, and then exhale when ready. This method can be cost-effective or pricey depending on what types of cartridges or vaporizers you get.

Edibles: This method is the simplest of all because all you have to do is eat the product and enjoy. Because you’re eating CBD-infused foods here, the effects are drawn-out over a longer period and the initial response happens a bit later than with the other forms. Edibles are great for subtlety and for those that want to be able to control their consumption.

Tinctures/Extracts/Liquid Oils: As dosages go, this type of CBD product is very easy to use because the recommended serving size is listed right on the packaging. If you know this, you’re ahead of the game because you can then determine how much you’re using and how you feel after with precision. For this method, all you have to do is place the correct amount of drops under your tongue and hold them there for at least 60 seconds. By doing this, the CBD can be absorbed by the blood vessels underneath your tongue instead of having to travel all throughout your body. Once the 60 seconds is up, just swallow.

 

4. Health Benefits?

Cannabinoids, specifically CBD, has a plethora of effects that are great on the body. They can aid in helping everything from inflammation to emotional disorders. While many of the beneficial cases out there include people with serious illnesses, CBD can also be used by healthy individuals to increase their quality of life.

Below are some conditions/illnesses that can be helped through CBD:

 

5. How Much CBD Oil Should I be Taking?

Once you figure out what you what your CBD oil to focus on and what effects you want to see on your body, dosages need to be figured out. Thankfully, Mayo Clinic has suggested dosages based on the opinions of publications, traditional usage, and expert opinions.

The chart below from Mayo Clinic provides the recommended dosages for specific illnesses and ailments:

  • Loss of Appetite in Cancer Patients: 2.5mg of THC (orally), with or without 1mg of CBD for six weeks. [S]
  • Chronic Pain: 2.5-20mg of CBD [with or without THC] (orally). [S]
  • Epilepsy: 200-300mg of CBD (orally) daily. [S]
  • Movement Problems Due to Huntington’s Disease: 10mg of CBD per kg of body weight daily for six weeks (orally). [S]
  • Sleep Disorders: 40mg-160mg of CBD (orally). [S]
  • Multiple Sclerosis (MS) symptoms: Cannabis plant extracts containing 2.5-120 milligrams of a THC/CBD combination daily for 2-15 weeks. Patients typically use eight sprays within any three hours, with a maximum of 48 sprays in any 24-hour period. [S]
  • Schizophrenia: 40-1,280mg oral CBD daily. [S]
  • Glaucoma: A single sublingual CBD dosage of 20-40mg (>40 mg may increase eye pressure). [S]


6. Finding a Brand to Trust with Dosages

The CBD market is already huge as it is and as consumers continue to invest in the products, the volume of CBD brands will continue to grow seemingly endlessly. With the amount of CBD brands available, a novice can become easily confused as to which one would work dosage-wise with the effects they are aiming for.

Users have to realize that vendors use different source materials (different strains, CBD-rich cannabis instead of hemp, etc.). This means that because they are all using different substances in their products, they have different ideas on the dosages their consumers should be taking. Some vendors would tell buyers to use excessive amounts while others would only suggest a fraction of what people would think to be effective for their needs.

People have to remember that not all CBD products are the same and slight, natural variations between them are normal because there are many factors that can affect the products (soil, weather, environment, etc.).

As stated earlier, through extensive analysis (CBD Oil Review), it has been found that 25mg of CBD, taken twice daily, seems to be the most successful dosage for many people as they can easily increase or decrease dosage amounts (by 25mg every 3-4 weeks) through time and experience.

7. One Important Factor that Affects Dosages

Despite all of the factors that affect dosages, genetics is the one that needs to be considered and examined the most.

Some people have mutations of the CNR1 gene, which is responsible for coding the CB1 receptor. This receptor found in cells throughout the body interacts with cannabinoids. IF there are issues with the CNR1 gene, the endocannabinoid system can function poorly, which means that people have to really figure out what dosage of CBD oil is appropriate for them.

Here is some information below about cellular-level factors that can affect CBD’s absorption into the body:

Certain lifestyle choices can directly effect CBD’s metabolism in the body. For example, THC increases the activity of CB1 receptors [1], while ethanol (alcohol) increases its expression [2]. If someone is smoking cannabis and drinking alcohol, the CBD effects can actually increase.

It’s the complete opposite with morphine and epinephrine because both decrease the activity of the CB1 receptor [3],[4]. This means that CBD could be useful in decreasing opiate usage.

Nicotine and exercise have similar effects as they both increase anandamide levels (similar to THC but we can synthesize this naturally in our brains), which is a natural CB1 receptor activator [5]. This means that being active and nicotine can increase CBD’s effects.

DHA (an omega-3 fatty acid) also increases CB1 receptors [6]. A diet rich in these fatty acids means that a person would be able to use less CBD oil.

Elevated glucocorticoids (i.e. cortisol) also reduces CB1 receptor density [7]. This means that people under chronic stress would most likely need to use more CBD oil to get the desired effects.

These are just the basics about genetics as CBD usage is still very new. Even with thorough information that already exists, it’s still best to consult with a medical expert or physician to understand what CBD oil is and to ask questions about any concerns you may have.

 

8. Overdosing on CBD

Despite what some may think, there is no concrete lethal dose of CBD. Those that are chronic users have been seen to have high dosages of up to 1500mg per day and can tolerate that amount well.

No matter what, it’s still important to speak to a physician about any concerns, especially in the beginning. There are some light risks that come with using CBD for extended periods of time or in high dosages including:

  • Dry Mouth
  • Lightheadedness
  • Sedation/Tiredness
  • Mild Low Blood Pressure
  • Reduced activity of B and T Cells
  • Decreased Fertilization
  • Reduced activity of Cytochrome P450 Enzyme (CYP450)
  • Reduced p-Glycoprotein activity

Fortunately, these side-effects are described for worst-case scenarios and aren’t typical.

While CBD is generally harmless, cannabinoids in general can have negative effects on the CYP450 enzyme, which is in the liver. Many pharmaceutical drugs (over 60%) actually undergo metabolism by this enzyme:

  • Sulfonylureas
  • PPIs
  • NSAIDs
  • Oral hypoglycemic agents
  • Beta Blockers
  • Antidepressants
  • Anti-epileptics
  • Antipsychotics
  • Anesthetics
  • Antibiotics
  • Immune modulators
  • HIV-antivirals
  • Prokinetics
  • Antihistamines
  • Calcium Channel Blockers
  • Steroids

It’s important to know also that the littlest things (even grapefruit juice) can affect the CYP450 enzyme in the same way as CBD. This is why it’s essential to talk to your physician before to research any drug interactions and to address additional questions. You working together with your doctor will always be best!

 

9. CBD isn’t Addictive

The question of whether CBD oil is addictive or not constantly pops up. Ultimately, the answer depends on your perspective.

Physically and chemically, no. CBD is not addictive in the same way as other substances are such as cocaine, alcohol, or heroin. It also cannot produce any physical withdrawal symptoms after someone ceases to use it. Ironically, CBD has been undergoing studies because of its ability to minimize withdrawal symptoms from heavier drugs such as opiates.

It’s actually people that become addicted to CBD themselves. Humans are able to get themselves addicted to almost anything (exercise, music, and sex are the most basic examples).

The people that take CBD daily to relieve their illnesses may find that their symptoms return shortly after missing a dose. This equates to the same effect of cold symptoms returning after the medicine taken wears off.

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Our mission is to educate and inform the Australian community about Medical Cannabis and Cannabidiol (CBD) products, so they are equipped with the correct information about the different types, products, dosages to make the right buying decisions for themselves or whom they care for. Learn more

Frequently Asked Questions

Cannabidiol (CBD for short) is a chemical compound that is extracted in oil form from cannabis. CBD is one of at least 113 active cannabinoids identified in cannabis. Learn More
There is scientific evidence and clinical trials that prove Medical Cannabis and CBD Oil can reduce and alleviate the symptoms of depression, anxiety, acne, heart disease, epilepsy, arthritis and much more
In Australia, you can obtain CBD Oil and medical cannabis products by getting in contact with specialist clinics, registered GPs, online methods. Read our page onwhere to buy CBD oil in Australia.
In 2016, the federal government introduced legislation to decriminalise the use and sale of medical marijuana. Each state of Australia has different laws and regulations that govern the use and access of medical cannabis. Learn More